DNMBP rabbit pAb

• Background :

  This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Description :

  This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],

• UniProt :

  Q6XZF7

• Swiss Prot :

  Q6XZF7

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from part region of human protein AA range: 940-990

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  173kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  173kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Golgi apparatus, Golgi stack . Cytoplasm, cytoskeleton . Cell junction, synapse . Cell junction . Localizes to the apical junction, colocalizes with TJP1. .

• Gene ID (Human) :

  23268