LRIG1 rabbit pAb

• Background :

  Domain:The LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted., function:Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation., induction:By EGF., similarity:Contains 17 LRR (leucine-rich) repeats., similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains., subunit:Interacts with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4., tissue specificity:Widely expressed.

• Description :

  Domain: The LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted. function: Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation. induction: By EGF. similarity: Contains 17 LRR (leucine-rich) repeats. similarity: Contains 3 Ig-like C2-type (immunoglobulin-like) domains. subunit: Interacts with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4. tissue specificity: Widely expressed.

• UniProt :

  Q96JA1

• Swiss Prot :

  Q96JA1

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from part region of human protein

• Target :

  LRIG1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  120kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  120kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Single-pass type I membrane protein .

• Gene ID (Human) :

  26018