Rac1/CDC42 (Phospho Ser71) rabbit pAb

• Product Name Alternative :

  Ras-related C3 botulinum toxin substrate 1 (Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1)

• UniProt :

  P63000/P15153/P60763/P60953

• Swiss Prot :

  P63000/P15153/P60763/P60953

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from human Rac1/CDC42 (Phospho Ser71)

• Target :

  Rac1/CDC42

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Buffer :

  -20°C/1 year

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasm . Cell projection, lamellipodium . Cell projection, dendrite . Cell junction, synapse . Nucleus . Inner surface of plasma membrane possibly with attachment requiring prenylation of the C-terminal cysteine (PubMed:1903399) . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065) . Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts. Localizes to the lamellipodium in a SH3RF1-dependent manner (By similarity) . In macrophages, cytoplasmic location increases upon CSF1 stimulation (By similarity) . Activation by GTP-binding promotes nuclear localization (PubMed:12551911) . .

• Other Product Names :

  Ras-related C3 botulinum toxin substrate 1 (Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1)

• Gene ID (Human) :

  5879