C-Jun (Hydroxylated-p244) rabbit pAb

• Background :

  Function:Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'., PTM:Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC., similarity:Belongs to the bZIP family., similarity:Belongs to the bZIP family. Jun subfamily., similarity:Contains 1 bZIP domain., subunit:Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity) . Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.

• Description :

  Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. PTM: Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC. similarity: Belongs to the bZIP family. similarity: Belongs to the bZIP family. Jun subfamily. similarity: Contains 1 bZIP domain. subunit: Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.

• UniProt :

  P05412

• Swiss Prot :

  P05412

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from human C-Jun (Hydroxylated-p244)

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:1000-2000 ELISA 1:5000-20000

• Molecular Weight :

  39-42kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  39-42kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus.

• Other Product Names :

  Transcription factor AP-1 (Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39)

• Gene ID (Human) :

  3725