ATG12 rabbit pAb

• Background :

  Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]) .[supplied by OMIM, Mar 2008]

• Description :

  Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al. 1998 [PubMed 9852036]). [supplied by OMIM, Mar 2008],

• UniProt :

  O94817

• Swiss Prot :

  O94817

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from human ATG12 AA range: 80-130

• Target :

  ATG12

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000

• Buffer :

  -20°C/1 year

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Preautophagosomal structure membrane ; Peripheral membrane protein . TECPR1 recruits the ATG12-ATG5 conjugate to the autolysosomal membrane.

• Gene ID (Human) :

  9140