Dab1 (Phospho Tyr220) rabbit pAb

• Background :

  Domain:The PID domain specifically binds to the Asn-Pro-Xaa-Tyr (P) motif found in many tyrosine-phosphorylated proteins., function:Adapter molecule functioning in neural development. May regulate SIAH1 activity., PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity) . Also phosphorylated on Ser-524 independently of reelin signaling., similarity:Contains 1 PID domain., subunit:Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity) . Interacts with LRP1.

• Description :

  Domain: The PID domain specifically binds to the Asn-Pro-Xaa-Tyr (P) motif found in many tyrosine-phosphorylated proteins. function: Adapter molecule functioning in neural development. May regulate SIAH1 activity. PTM: Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling. similarity: Contains 1 PID domain. subunit: Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.

• UniProt :

  O75553

• Swiss Prot :

  O75553

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from human Dab1 (Phospho Tyr220)

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:1000-2000 ELISA 1:5000-20000

• Molecular Weight :

  60kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  60kD

• Fragment :

  IgG

• Other Product Names :

  Disabled homolog 1

• Gene ID (Human) :

  1600