Cav1.3 rabbit pAb

• Background :

  Calcium voltage-gated channel subunit alpha1 D (CACNA1D) Homo sapiens Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

• Description :

  Calcium voltage-gated channel subunit alpha1 D (CACNA1D) Homo sapiens Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],

• UniProt :

  Q01668

• Swiss Prot :

  Q01668

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthetic Peptide of Cav1.3 AA range: 1060-1140

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF

• Concentration :

  1 mg/ml

• Dilution :

  IHC 1:100-200

• Molecular Weight :

  245kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  245kD

• Fragment :

  IgG

• Subcellular Location :

  Membrane ; Multi-pass membrane protein .

• Other Product Names :

  Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2; Voltage-gated calcium channel subunit alpha Cav1.3)

• Gene ID (Human) :

  776