PPAR α (Phospho Ser21) rabbit pAb

• Background :

  Function:Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids., online information:Peroxisome proliferator-activated receptor entry, similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily., similarity:Contains 1 nuclear receptor DNA-binding domain., subunit:Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13., tissue specificity:Skeletal muscle, liver, heart and kidney.

• Description :

  Function: Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. online information: Peroxisome proliferator-activated receptor entry, similarity: Belongs to the nuclear hormone receptor family. NR1 subfamily. similarity: Contains 1 nuclear receptor DNA-binding domain. subunit: Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13. tissue specificity: Skeletal muscle, liver, heart and kidney.

• Product Name Alternative :

  Peroxisome proliferator-activated receptor alpha (PPAR-alpha; Nuclear receptor subfamily 1 group C member 1)

• UniProt :

  Q07869

• Swiss Prot :

  Q07869

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from human PPAR α (Phospho Ser21)

• Target :

  PPAR α

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Buffer :

  -20°C/1 year

• Molecular Weight :

  52kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  52kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus.

• Other Product Names :

  Peroxisome proliferator-activated receptor alpha (PPAR-alpha; Nuclear receptor subfamily 1 group C member 1)

• Gene ID (Human) :

  5465