FKBP1B Rabbit pAb

• Background :

  The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]

• Description :

  The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B; EC 5.2.1.8;12.6 kDa FK506-binding protein;12.6 kDa FKBP; FKBP-12.6; FK506-binding protein 1B; FKBP-1B; Immunophilin FKBP12.6; Rotamase; h-FKBP-12)

• UniProt :

  P68106

• Swiss Prot :

  P68106

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from human FKBP1B AA range: 35-85

• Target :

  FKBP1B

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  IHC-p 1:50-200, ELISA (peptide) 1:5000-20000

• Buffer :

  -20°C/1 year

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Sarcoplasmic reticulum .

• Other Product Names :

  Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B; EC 5.2.1.8;12.6 kDa FK506-binding protein;12.6 kDa FKBP; FKBP-12.6; FK506-binding protein 1B; FKBP-1B; Immunophilin FKBP12.6; Rotamase; h-FKBP-12)

• Gene ID (Human) :

  2281