APOC1 Rabbit pAb

• Background :

  This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016]

• Description :

  This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016],

• Product Name Alternative :

  Apolipoprotein C-I (Apo-CIB; ApoC-IB; Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I (Apo-CIB'; ApoC-IB') ]

• UniProt :

  P02654

• Swiss Prot :

  P02654

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from human APOC1 AA range: 1-50

• Target :

  APOC1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  IHC-p 1:50-200, ELISA (peptide) 1:5000-20000

• Buffer :

  -20°C/1 year

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Secreted .

• Other Product Names :

  Apolipoprotein C-I (Apo-CIB; ApoC-IB; Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I (Apo-CIB'; ApoC-IB') ]

• Gene ID (Human) :

  341