TRI37 rabbit pAb

• Background :

  This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. [provided by RefSeq, Mar 2016]

• Description :

  This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. [provided by RefSeq, Mar 2016],

• Product Name Alternative :

  E3 ubiquitin-protein ligase TRIM37 (EC 6.3.2.-) (Mulibrey nanism protein) (Tripartite motif-containing protein 37)

• UniProt :

  O94972

• Swiss Prot :

  O94972

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from human TRI37 AA range: 315-365

• Target :

  TRI37

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  105kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  105kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, perinuclear region . Peroxisome . Found in vesicles of the peroxisome. Aggregates as aggresomes, a perinuclear region where certain misfolded or aggregated proteins are sequestered for proteasomal degradation. .

• Other Product Names :

  E3 ubiquitin-protein ligase TRIM37 (EC 6.3.2.-) (Mulibrey nanism protein) (Tripartite motif-containing protein 37)

• Gene ID (Human) :

  4591