Cav2.2 rabbit pAb

• Background :

  Calcium voltage-gated channel subunit alpha1 B (CACNA1B) Homo sapiens The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

• Description :

  Calcium voltage-gated channel subunit alpha1 B (CACNA1B) Homo sapiens The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],

• UniProt :

  Q00975

• Swiss Prot :

  Q00975

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthetic Peptide of Cav2.2 AA range: 230-310

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF

• Concentration :

  1 mg/ml

• Dilution :

  IHC 1:50-100

• Molecular Weight :

  263kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  263kD

• Fragment :

  IgG

• Subcellular Location :

  Membrane ; Multi-pass membrane protein .

• Other Product Names :

  Voltage-dependent N-type calcium channel subunit alpha-1B (Brain calcium channel III; BIII; Calcium channel, L type, alpha-1 polypeptide isoform 5; Voltage-gated calcium channel subunit alpha Cav2.2)

• Gene ID (Human) :

  774