GABA A Receptor α2 rabbit pAb

• Background :

  GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

• Description :

  GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013],

• UniProt :

  P47869

• Swiss Prot :

  P47869

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthetic Peptide of GABA A Receptor α2

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:1000-2000, IHC 1:100-200

• Molecular Weight :

  51kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  51kD

• Fragment :

  IgG

• Subcellular Location :

  Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane . Cell projection, dendrite .

• Other Product Names :

  Gamma-aminobutyric acid receptor subunit alpha-2 (GABA (A) receptor subunit alpha-2)

• Gene ID (Human) :

  282236