Jak1 (phospho-Tyr1034/1035) rabbit pAb

• Background :

  This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

• Description :

  This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

• Product Name Alternative :

  Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)

• UniProt :

  P23458

• Swiss Prot :

  P23458

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized phosho peptide around human Jak1 (Tyr1034 and 1035)

• Target :

  JAK1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Buffer :

  -20°C/1 year

• Molecular Weight :

  132kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  132kD

• Fragment :

  IgG

• Subcellular Location :

  Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.

• Other Product Names :

  Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)

• Gene ID (Human) :

  3716