FXL12 rabbit pAb

• Background :

  Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .[supplied by OMIM, Mar 2008]

• Description :

  Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al. 2004 [PubMed 15520277]). [supplied by OMIM, Mar 2008],

• UniProt :

  Q9NXK8

• Swiss Prot :

  Q9NXK8

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from human FXL12 AA range: 8-58

• Target :

  FXL12

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000

• Buffer :

  -20°C/1 year

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Ubiquitin ligase complex, cytoplasm, integral component of membrane

• Gene ID (Human) :

  54850