Tuberin/TSC2 (phospho-Ser664) rabbit pAb

• Background :

  Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Description :

  Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

• UniProt :

  P49815

• Swiss Prot :

  P49815

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized phosho peptide around human Tuberin (Ser664)

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:1000-2000

• Molecular Weight :

  200kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  200kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.

• Other Product Names :

  Tuberin (Tuberous sclerosis 2 protein)

• Gene ID (Human) :

  7249