Jak3 (phospho-Tyr980/981) rabbit pAb

• Background :

  The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) . [provided by RefSeq, Jul 2008]

• Description :

  The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in Cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)

• UniProt :

  P52333

• Swiss Prot :

  P52333

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized phosho peptide around human Jak3 (Tyr980 and 981)

• Target :

  JAK3

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Buffer :

  -20°C/1 year

• Molecular Weight :

  125kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  125kD

• Fragment :

  IgG

• Subcellular Location :

  Endomembrane system ; Peripheral membrane protein . Cytoplasm .

• Other Product Names :

  Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)

• Gene ID (Human) :

  3718