Myosin Heavy Chain Mouse mAb

• Background :

  Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2) . Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies.

• Description :

  Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies.

• Product Name Alternative :

  Bsh, CG17927, Dm II, Dmel\CG17927, DmMHC, DROMHC, DroMII, FBgn0002741, Ifm (2) 2, l (2) 36Ae, l (2) k10423, l (2) M66, Mhc, Mhc36B, mMHC, MRP, Myo, Myosin heavy chain, Nup, Sht, sMHC, Stp

• UniProt :

  P12882

• Swiss Prot :

  P12882

• Reactivity :

  Human, Mouse, Rat, Fruit Fly, Nematode

• Immunogen :

  Synthetic Peptide

• Clonality :

  Monoclonal

• Source :

  Mouse

• Applications :

  IHC, IF

• Concentration :

  1mg/mL

• Dilution :

  IHC 1:200 IF 1:100

• Buffer :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Molecular Weight :

  220kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight :

  220kDa

• Fragment :

  IgG1

• Subcellular Location :

  Cytoplasm, Thick filament

• Other Product Names :

  Bsh, CG17927, Dm II, Dmel\CG17927, DmMHC, DROMHC, DroMII, FBgn0002741, Ifm (2) 2, l (2) 36Ae, l (2) k10423, l (2) M66, Mhc, Mhc36B, mMHC, MRP, Myo, Myosin heavy chain, Nup, Sht, sMHC, Stp

• Gene ID (Human) :

  4619