ATG13 Rabbit pAb

• Background :

  Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.

• Description :

  Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.

• Product Name Alternative :

  KIAA0652, Apg13, Autophagy-related protein 13 antibody

• UniProt :

  O75143

• Swiss Prot :

  O75143

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant Protein

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC

• Concentration :

  1mg/mL

• Dilution :

  IHC 1:100-200

• Buffer :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Molecular Weight :

  57kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight :

  57kDa

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm

• Other Product Names :

  KIAA0652, Apg13, Autophagy-related protein 13 antibody

• Gene ID (Human) :

  9776