GM2/GD2 synthase rabbit pAb

• Background :

  Beta-1,4-N-acetyl-galactosaminyltransferase 1 (B4GALNT1) Homo sapiens GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G (M2) and G (D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G (M3) and G (D3) by a beta-1,4 linkage, resulting in the synthesis of G (M2) and G (D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]

• Description :

  Beta-1, 4-N-acetyl-galactosaminyltransferase 1 (B4GALNT1) Homo sapiens GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G (M2) and G (D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G (M3) and G (D3) by a Beta-1, 4 linkage, resulting in the synthesis of G (M2) and G (D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013],

• Product Name Alternative :

  B4GALNT1; GALGT; SIAT2; Beta-1; 4 N-acetylgalactosaminyltransferase 1; (N-acetylneuraminyl) -galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T

• UniProt :

  Q00973

• Swiss Prot :

  Q00973

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human B4GALNT1. AA range:281-330

• Target :

  GM2/GD2 synthase

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  60kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  60kD

• Fragment :

  IgG

• Subcellular Location :

  Golgi apparatus membrane ; Single-pass type II membrane protein .

• Other Product Names :

  B4GALNT1; GALGT; SIAT2; Beta-1; 4 N-acetylgalactosaminyltransferase 1; (N-acetylneuraminyl) -galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T

• Gene ID (Human) :

  2583