MLK4 rabbit pAb

• Background :

  Catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation., function:Activates the JUN N-terminal pathway., PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation., similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily., similarity:Contains 1 protein kinase domain., similarity:Contains 1 SH3 domain., subunit:Homodimer.

• Description :

  Catalytic activity: ATP + a protein = ADP + a phosphoprotein. Cofactor: Magnesium. enzyme regulation: Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation. function: Activates the JUN N-terminal pathway. PTM: Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. similarity: Contains 1 protein kinase domain. similarity: Contains 1 SH3 domain. subunit: Homodimer.

• Product Name Alternative :

  MLK4; KIAA1804; Mitogen-activated protein kinase kinase kinase MLK4; Mixed lineage kinase 4

• UniProt :

  Q5TCX8

• Swiss Prot :

  Q5TCX8

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human MAP3KL4. AA range:631-680

• Target :

  MLK4

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  110kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  110kD

• Fragment :

  IgG

• Subcellular Location :

  Intracellular

• Other Product Names :

  MLK4; KIAA1804; Mitogen-activated protein kinase kinase kinase MLK4; Mixed lineage kinase 4

• Gene ID (Human) :

  84451