Myp rabbit pAb

• Background :

  NOL3 encodes an anti-apoptotic protein nucleolar protein 3 that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for NOL3.

• Description :

  NOL3 encodes an anti-apoptotic protein nucleolar protein 3 that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for NOL3.

• Product Name Alternative :

  Myp; NOL3; Nop30; Nucleolar protein 3; apoptosis repressor ARC; apoptosis repressor with CARD; apoptosis repressor with caspase recruitment domain (CARD) ; muscle-enriched cytoplasmic protein; nucleolar protein of 30 kDa

• UniProt :

  O60936-2

• Swiss Prot :

  O60936-2

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human ARC. AA range:159-208

• Target :

  Myp

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  28kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  28kD

• Fragment :

  IgG

• Subcellular Location :

  [Isoform 1]: Nucleus, nucleolus . The SR-rich C-terminus mediates nuclear localization. .; [Isoform 3]: Cytoplasm .; [Isoform 2]: Cytoplasm . Mitochondrion . Sarcoplasmic reticulum . Membrane ; Lipid-anchor . Phosphorylation at Thr-149 results in translocation to mitochondria. Colocalized with mitochondria in response to oxidative stress. .

• Other Product Names :

  Myp; NOL3; Nop30; Nucleolar protein 3; apoptosis repressor ARC; apoptosis repressor with CARD; apoptosis repressor with caspase recruitment domain (CARD) ; muscle-enriched cytoplasmic protein; nucleolar protein of 30 kDa

• Gene ID (Human) :

  8996