STAM2 rabbit pAb

• Background :

  The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM) . Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008]

• Description :

  The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of Cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to Cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon Cytokine stimulation. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  STAM2; HBP; Signal transducing adapter molecule 2; STAM-2; Hrs-binding protein

• UniProt :

  O75886

• Swiss Prot :

  O75886

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human STAM2. AA range:161-210

• Target :

  STAM2

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  58kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  58kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .

• Other Product Names :

  STAM2; HBP; Signal transducing adapter molecule 2; STAM-2; Hrs-binding protein

• Gene ID (Human) :

  10254