TrxR2 rabbit pAb

• Background :

  Thioredoxin reductase 2 (TXNRD2) Homo sapiens This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2013]

• Description :

  Thioredoxin reductase 2 (TXNRD2) Homo sapiens This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2013],

• UniProt :

  Q9NNW7

• Swiss Prot :

  Q9NNW7

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human TRXR2. AA range:471-520

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  56kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  56kD

• Fragment :

  IgG

• Subcellular Location :

  Mitochondrion .

• Other Product Names :

  TXNRD2; KIAA1652; TRXR2; Thioredoxin reductase 2; mitochondrial; Selenoprotein Z; SelZ; TR-beta; Thioredoxin reductase TR3

• Gene ID (Human) :

  10587