UBE4A rabbit pAb

• Background :

  This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]

• Description :

  This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011],

• Product Name Alternative :

  UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A

• UniProt :

  Q14139

• Swiss Prot :

  Q14139

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from the N-terminal region of human UBE4A.

• Target :

  UBE4A

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  122kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  122kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm .

• Other Product Names :

  UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A

• Gene ID (Human) :

  9354