Fractalkine rabbit pAb

• Background :

  Function:The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1., induction:By TNF and IL-1 in pulmonary endothelial cells and umbilical vein endothelial cells., online information:CX3CL1 entry, PTM:A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form., similarity:Belongs to the intercrine delta family., subunit:Monomer., tissue specificity:Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.

• Description :

  Function: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. induction: By TNF and IL-1 in pulmonary endothelial cells and umbilical vein endothelial cells. online information: CX3CL1 entry, PTM: A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form. similarity: Belongs to the intercrine delta family. subunit: Monomer. tissue specificity: Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.

• Product Name Alternative :

  CX3CL1; FKN; NTT; SCYD1; A-152E5.2; Fractalkine; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1

• UniProt :

  P78423

• Swiss Prot :

  P78423

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from the Internal region of human CX3CL1. AA range:231-280

• Target :

  Fractalkine

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  42kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  42kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Single-pass type I membrane protein .; [Processed fractalkine]: Secreted .

• Other Product Names :

  CX3CL1; FKN; NTT; SCYD1; A-152E5.2; Fractalkine; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1

• Gene ID (Human) :

  6376