Jagged1 rabbit pAb

• Background :

  The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]

• Description :

  The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  JAG1; JAGL1; Protein jagged-1; Jagged1; hJ1; CD339

• UniProt :

  P78504

• Swiss Prot :

  P78504

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from the Internal region of human JAG1. AA range:981-1030

• Target :

  Jagged1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IF; WB; IHC; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  140kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  140kD

• Fragment :

  IgG

• Subcellular Location :

  Membrane; Single-pass type I membrane protein.

• Other Product Names :

  JAG1; JAGL1; Protein jagged-1; Jagged1; hJ1; CD339

• Gene ID (Human) :

  182