Rag B rabbit pAb

• Background :

  Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3) . Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

• Description :

  Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008],

• UniProt :

  Q5VZM2

• Swiss Prot :

  Q5VZM2

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from Rag B . at AA range: 50-130

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Lysosome .

• Other Product Names :

  RRAGB; Ras-related GTP-binding protein B; Rag B; RagB

• Gene ID (Human) :

  10325