PP4R2 rabbit pAb

• Background :

  The protein encoded by this gene is a regulatory subunit of the serine/threonine-protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

• Description :

  The protein encoded by this gene is a regulatory subunit of the serine/threonine-protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],

• UniProt :

  Q9NY27

• Swiss Prot :

  Q9NY27

• Reactivity :

  Human; Monkey

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human PPP4R2. AA range:171-220

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

• Molecular Weight :

  50kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  50kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Ionizing radiation induces relocalization to nuclear foci and colocalization with RPA2.

• Other Product Names :

  PPP4R2; SBBI57; Serine/threonine-protein phosphatase 4 regulatory subunit 2

• Gene ID (Human) :

  151987