LARG rabbit pAb

• Background :

  Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

• Description :

  Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

• Product Name Alternative :

  ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF

• UniProt :

  Q9NZN5

• Swiss Prot :

  Q9NZN5

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498

• Target :

  LARG

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Buffer :

  -20°C/1 year

• Molecular Weight :

  173kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  173kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Membrane . Translocated to the membrane upon stimulation. .

• Other Product Names :

  ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF

• Gene ID (Human) :

  23365