Rab 38 rabbit pAb

• Background :

  Function:May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1., PTM:Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated., similarity:Belongs to the small GTPase superfamily. Rab family., tissue specificity:Expressed in melanocytes.

• Description :

  Function: May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. PTM: Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated. similarity: Belongs to the small GTPase superfamily. Rab family. tissue specificity: Expressed in melanocytes.

• UniProt :

  P57729

• Swiss Prot :

  P57729

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human RAB38. AA range:80-129

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Molecular Weight :

  26kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  26kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome membrane . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211) . The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991) . .

• Other Product Names :

  RAB38; Ras-related protein Rab-38; Melanoma antigen NY-MEL-1

• Gene ID (Human) :

  23682