Gas8 rabbit pAb

• Background :

  This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]

• Description :

  This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013],

• UniProt :

  O95995

• Swiss Prot :

  O95995

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from the Internal region of human Gas8.

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF; WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight :

  56kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  56kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Cytoplasm, cytoskeleton . Cell projection, cilium, flagellum . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, cilium basal body . Golgi apparatus . Cell projection, cilium . Cytoplasm, cytoskeleton, flagellum axoneme . Associates with microtubules (PubMed:10969087) . Localized to the cytoplasm of round spermatids, the tails of elongating spermatids, and mature spermatid tail bundles protruding into the lumen, and in the flagellum of epididymal spermatozoa (By similarity) . .

• Other Product Names :

  GAS8; GAS11; Growth arrest-specific protein 8; GAS-8; Growth arrest-specific protein 11; GAS-11

• Gene ID (Human) :

  2622