Gγ 5 rabbit pAb

• Background :

  G protein subunit gamma 5 (GNG5) Homo sapiens G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010]

• Description :

  G protein subunit gamma 5 (GNG5) Homo sapiens G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al. 1995) [PubMed 7606925]. [supplied by OMIM, Nov 2010],

• Product Name Alternative :

  GNG5; GNGT5; Guanine nucleotide-binding protein G (I) /G (S) /G (O) subunit gamma-5

• UniProt :

  P63218

• Swiss Prot :

  P63218

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human GNG5. AA range:10-59

• Target :

  Gγ 5

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Lipid-anchor ; Cytoplasmic side .

• Other Product Names :

  GNG5; GNGT5; Guanine nucleotide-binding protein G (I) /G (S) /G (O) subunit gamma-5

• Gene ID (Human) :

  2787