Epsin 3 rabbit pAb

• Background :

  Induction:In keratinocytes, by wounding or contact with collagen., similarity:Belongs to the epsin family., similarity:Contains 1 ENTH (epsin N-terminal homology) domain., similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats., subcellular location:Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus., tissue specificity:Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.

• Description :

  Induction: In keratinocytes, by wounding or contact with collagen. similarity: Belongs to the epsin family. similarity: Contains 1 ENTH (epsin N-terminal homology) domain. similarity: Contains 2 UIM (ubiquitin-interacting motif) repeats. subcellular location: Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus. tissue specificity: Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.

• UniProt :

  Q9H201

• Swiss Prot :

  Q9H201

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human EPN3. AA range:401-450

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  68kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  68kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Cytoplasm, perinuclear region . Cytoplasmic vesicle, clathrin-coated vesicle . Nucleus . Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.

• Other Product Names :

  EPN3; Epsin-3; EPS-15-interacting protein 3

• Gene ID (Human) :

  55040