Rab 1B rabbit pAb

• Background :

  Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]) .[supplied by OMIM, Jan 2009]

• Description :

  Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al. 1997 [PubMed 9030196]; Alvarez et al. 2003 [PubMed 12802079]). [supplied by OMIM, Jan 2009],

• Product Name Alternative :

  RAB1B; Ras-related protein Rab-1B

• UniProt :

  Q9H0U4

• Swiss Prot :

  Q9H0U4

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from Rab 1B . at AA range: 50-130

• Target :

  Rab 1B

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  22kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  22kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Membrane ; Lipid-anchor ; Cytoplasmic side . Preautophagosomal structure membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, perinuclear region . Targeted by REP1 to membranes of specific subcellular compartments including endoplasmic reticulum, Golgi apparatus, and intermediate vesicles between these two compartments (PubMed:11389151) . In the GDP-form, colocalizes with GDI in the cytoplasm (PubMed:11389151) . Co-localizes with MTMR6 to the endoplasmic reticulum-Golgi intermediate compartment and to the peri-Golgi region (By similarity) . .

• Other Product Names :

  RAB1B; Ras-related protein Rab-1B

• Gene ID (Human) :

  81876