NFATc2IP rabbit pAb

• Background :

  Function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production., PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production., similarity:Contains 1 ubiquitin-like domain., subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus., subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.

• Description :

  Function: Plays a role in the inducible expression of Cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production. PTM: Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented Cytokine production. similarity: Contains 1 ubiquitin-like domain. subcellular location: TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. subunit: Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.

• UniProt :

  Q8NCF5

• Swiss Prot :

  Q8NCF5

• Reactivity :

  Human; Rat; Mouse; ; Fish

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human NFATC2IP. AA range:151-200

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Molecular Weight :

  48kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  48kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus . Cytoplasm . TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. .

• Other Product Names :

  NFATC2IP; NIP45; NFATC2-interacting protein; 45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; Nuclear factor of activated T-cells; cytoplasmic 2-interacting protein

• Gene ID (Human) :

  84901