Dyrk1B rabbit pAb

• Background :

  This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

• Description :

  This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],

• UniProt :

  Q9Y463

• Swiss Prot :

  Q9Y463

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human DYR1B. AA range:331-380

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight :

  70kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  70kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus . Nucleus, nucleolus . Chromosome . Localizes to sites of double-strand breaks (DSBs) following DNA damage. .

• Other Product Names :

  DYRK1B; MIRK; Dual specificity tyrosine-phosphorylation-regulated kinase 1B; Minibrain-related kinase; Mirk protein kinase

• Gene ID (Human) :

  9149