MAD2L1BP rabbit pAb

• Background :

  The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1) . MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

• Description :

  The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  MAD2L1BP; CMT2; KIAA0110; MAD2L1-binding protein; Caught by MAD2 protein

• UniProt :

  Q15013

• Swiss Prot :

  Q15013

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from MAD2L1BP . at AA range: 10-90

• Target :

  MAD2L1BP

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  31kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  31kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus. Cytoplasm, cytoskeleton, spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.

• Other Product Names :

  MAD2L1BP; CMT2; KIAA0110; MAD2L1-binding protein; Caught by MAD2 protein

• Gene ID (Human) :

  9587