Topo IIIα rabbit pAb

• Background :

  This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

• Description :

  This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

• Product Name Alternative :

  TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha

• UniProt :

  Q13472

• Swiss Prot :

  Q13472

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from Topo IIIα . at AA range: 350-430

• Target :

  Topo IIIα

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  115kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  115kD

• Fragment :

  IgG

• Subcellular Location :

  Mitochondrion matrix .

• Other Product Names :

  TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha

• Gene ID (Human) :

  7156