MYOZ2 rabbit pAb

• Background :

  The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011]

• Description :

  The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011],

• Product Name Alternative :

  MYOZ2 C4orf5

• UniProt :

  Q9NPC6

• Swiss Prot :

  Q9NPC6

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from the Internal region of human MYOZ2. AA range:21-70

• Target :

  MYOZ2

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  30kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  30kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, myofibril, sarcomere, Z line . Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle. .

• Other Product Names :

  MYOZ2 C4orf5

• Gene ID (Human) :

  51778