IL-19 rabbit pAb

• Background :

  The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3) . A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]

• Description :

  The protein encoded by this gene is a Cytokine that belongs to the IL10 Cytokine subfamily. This Cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar Cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this Cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008],

• UniProt :

  Q9UHD0

• Swiss Prot :

  Q9UHD0

• Reactivity :

  Human; Rat

• Immunogen :

  Synthetic peptide from human protein at AA range: 51-100

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000

• Molecular Weight :

  20kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  20kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted.

• Other Product Names :

  Interleukin-19 (IL-19; Melanoma differentiation-associated protein-like protein; NG.1)

• Gene ID (Human) :

  29949