CERU rabbit pAb

• Background :

  The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe (II) transferrin to Fe (III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]

• Description :

  The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe (II)transferrin to Fe (III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012],

• UniProt :

  P00450

• Swiss Prot :

  P00450

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from part region of human protein

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  117kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  117kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted. Colocalizes with GCP1 in secretory intracellular compartments. .

• Gene ID (Human) :

  1356