DLG3 rabbit pAb

• Background :

  This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]

• Description :

  This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009],

• UniProt :

  Q92796

• Swiss Prot :

  Q92796

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from part region of human protein

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  89kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  89kD

• Fragment :

  IgG

• Subcellular Location :

  Extracellular space, cytoplasm, plasma membrane, bicellular tight junction, ionotropic glutamate receptor complex, postsynaptic density, basolateral plasma membrane, growth cone, AMPA glutamate receptor complex, neuronal cell body, d

• Gene ID (Human) :

  1741