CENPT rabbit pAb

• Background :

  The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128) . CENPT is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]) .[supplied by OMIM, Mar 2008]

• Description :

  The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an additional factor required for centromere assembly (Foltz et al. 2006 [PubMed 16622419]). [supplied by OMIM, Mar 2008],

• UniProt :

  Q96BT3

• Swiss Prot :

  Q96BT3

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from human protein . at AA range: 20-100

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  61kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  61kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus. Chromosome, centromere . Chromosome, centromere, kinetochore . Constitutively localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis. Localizes to the inner kinetochore, and may connect it to the outer kinetochore via its N-terminus. .

• Gene ID (Human) :

  80152