BAMBI rabbit pAb

• Background :

  BMP and activin membrane bound inhibitor (BAMBI) Homo sapiens This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]

• Description :

  BMP and activin membrane bound inhibitor (BAMBI) Homo sapiens This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008],

• UniProt :

  Q13145

• Swiss Prot :

  Q13145

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from part region of human protein

• Target :

  BAMBI

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  28kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  28kD

• Fragment :

  IgG

• Subcellular Location :

  Membrane ; Single-pass type I membrane protein .

• Gene ID (Human) :

  25805