NALP2 rabbit pAb

• Background :

  NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030) . They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]) .[supplied by OMIM, Mar 2008]

• Description :

  NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al. 2003 [PubMed 12563287]). [supplied by OMIM, Mar 2008],

• UniProt :

  Q9NX02

• Swiss Prot :

  Q9NX02

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from human protein . at AA range: 620-700

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  116kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  116kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm .

• Gene ID (Human) :

  55655