RAGP1 rabbit pAb

• Background :

  This gene encodes a protein that associates with the nuclear pore complex and participates in the regulation of nuclear transport. The encoded protein interacts with Ras-related nuclear protein 1 (RAN) and regulates guanosine triphosphate (GTP) -binding and exchange. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

• Description :

  This gene encodes a protein that associates with the nuclear pore complex and participates in the regulation of nuclear transport. The encoded protein interacts with Ras-related nuclear protein 1 (RAN) and regulates guanosine triphosphate (GTP)-binding and exchange. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

• UniProt :

  P46060

• Swiss Prot :

  P46060

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from part region of human protein

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  64kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  64kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Nucleus, nucleoplasm . Nucleus envelope . Chromosome, centromere, kinetochore . Cytoplasm, cytoskeleton, spindle . Cytoplasmic during interphase. Detected at the nuclear envelope during interphase (PubMed:11854305, PubMed:15037602) . Targeted to the nuclear pores after sumoylation (PubMed:11854305) . During mitosis, associates with mitotic spindles, but is essentially not detected at the spindle poles (PubMed:11854305, PubMed:15037602) . Association with kinetochores appears soon after nuclear envelope breakdown and persists until late anaphase (PubMed:11854305) . Mitotic location also requires sumoylation (PubMed:11854305) . .

• Gene ID (Human) :

  5905