LCTL rabbit pAb

• Background :

  This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582) . Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

• Description :

  This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],

• Product Name Alternative :

  Lactase-like protein (Klotho/lactase-phlorizin hydrolase-related protein)

• UniProt :

  Q6UWM7

• Swiss Prot :

  Q6UWM7

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from human LCTL AA range: 450-500

• Target :

  LCTL

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  60kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  60kD

• Fragment :

  IgG

• Subcellular Location :

  Endoplasmic reticulum membrane ; Single-pass membrane protein .

• Other Product Names :

  Lactase-like protein (Klotho/lactase-phlorizin hydrolase-related protein)

• Gene ID (Human) :

  197021