PERM (light chain, Cleaved-Gly278) rabbit pAb

• Background :

  Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]

• Description :

  Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014],

• UniProt :

  P05164

• Swiss Prot :

  P05164

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from human PERM (light chain, Cleaved-Gly278)

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Molecular Weight :

  12 84 89kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  12 84 89kD

• Fragment :

  IgG

• Subcellular Location :

  Lysosome.

• Other Product Names :

  Myeloperoxidase (MPO; EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain]

• Gene ID (Human) :

  4353