NRAM2 rabbit pAb

• Background :

  This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]

• Description :

  This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],

• Product Name Alternative :

  Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1)

• UniProt :

  P49281

• Swiss Prot :

  P49281

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from human NRAM2 AA range: 474-524

• Target :

  NRAM2

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  60kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  60kD

• Fragment :

  IgG

• Subcellular Location :

  [Isoform 2]: Cell membrane ; Multi-pass membrane protein . Early endosome .; Endosome membrane ; Multi-pass membrane protein . Mitochondrion outer membrane ; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein . Also found in extracellular vesicles different from exosomes. .

• Other Product Names :

  Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1)

• Gene ID (Human) :

  4891